Found 7 hits for monomerid = 86741 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H2 Receptor
(Homo sapiens (Human)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 317: 1262-8 (2006)
Article DOI: 10.1124/jpet.106.102897 BindingDB Entry DOI: 10.7270/Q2X63KHZ |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 138 | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity |
J Med Chem 51: 7193-204 (2009)
Article DOI: 10.1021/jm800841w BindingDB Entry DOI: 10.7270/Q2RN38T6 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM86741
(UR-AK59)Show SMILES CC(C1CCCCC1)C(=O)NC(N)=NCCCc1cnc[nH]1 |w:13.14| Show InChI InChI=1S/C16H27N5O/c1-12(13-6-3-2-4-7-13)15(22)21-16(17)19-9-5-8-14-10-18-11-20-14/h10-13H,2-9H2,1H3,(H,18,20)(H3,17,19,21,22) | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a |
University of Regensburg
Curated by ChEMBL
| Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced positive chronotropic activity |
J Med Chem 51: 7193-204 (2009)
Article DOI: 10.1021/jm800841w BindingDB Entry DOI: 10.7270/Q2RN38T6 |
More data for this Ligand-Target Pair | |