BDBM87227 3,4-bis(fluoranyl)-N-[(2S)-1-[4-(6-fluoranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid::3,4-difluoro-N-[(1S)-2-[4-(6-fluoro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]benzamide;2,2,2-trifluoroacetic acid::3,4-difluoro-N-[(2S)-1-[4-(6-fluoro-2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]propan-2-yl]benzamide;2,2,2-trifluoroacetic acid::3,4-difluoro-N-[(2S)-1-[4-(6-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-trifluoroacetic acid::VU0359568-1::cid_53470209

SMILES: C[C@@H](CN1CCC(CC1)n1c2cc(F)ccc2[nH]c1=O)NC(=O)c1ccc(F)c(F)c1

InChI Key: InChIKey=HPTPLUVUBNHEQY-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 87227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM87227 (3,4-bis(fluoranyl)-N-[(2S)-1-[4-(6-fluoranyl-2-oxi...) Show SMILES C[C@@H](CN1CCC(CC1)n1c2cc(F)ccc2[nH]c1=O)NC(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C22H23F3N4O2/c1-13(26-21(30)14-2-4-17(24)18(25)10-14)12-28-8-6-16(7-9-28)29-20-11-15(23)3-5-19(20)27-22(29)31/h2-5,10-11,13,16H,6-9,12H2,1H3,(H,26,30)(H,27,31)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Specialized Chemistry Center Curated by PubChem BioAssay					Assay Description Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CNK
					More data for this Ligand-Target Pair
Phospholipase D2 (PLD2) (Homo sapiens (Human))	BDBM87227 (3,4-bis(fluoranyl)-N-[(2S)-1-[4-(6-fluoranyl-2-oxi...) Show SMILES C[C@@H](CN1CCC(CC1)n1c2cc(F)ccc2[nH]c1=O)NC(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C22H23F3N4O2/c1-13(26-21(30)14-2-4-17(24)18(25)10-14)12-28-8-6-16(7-9-28)29-20-11-15(23)3-5-19(20)27-22(29)31/h2-5,10-11,13,16H,6-9,12H2,1H3,(H,26,30)(H,27,31)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Specialized Chemistry Center Curated by PubChem BioAssay					Assay Description Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21R6P4V
					More data for this Ligand-Target Pair