BDBM8748 1-[(4-phenylphenyl)methyl]-4-(thiophen-3-yl)-1H-imidazole::Disubstituted imidazole 27

SMILES: C(c1ccc(cc1)-c1ccccc1)n1cnc(c1)-c1ccsc1

InChI Key: InChIKey=LVMVRNXVOMGHBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (FabI) (Escherichia coli)	BDBM8748 (1-[(4-phenylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...) Show SMILES C(c1ccc(cc1)-c1ccccc1)n1cnc(c1)-c1ccsc1 Show InChI InChI=1S/C20H16N2S/c1-2-4-17(5-3-1)18-8-6-16(7-9-18)12-22-13-20(21-15-22)19-10-11-23-14-19/h1-11,13-15H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	30
GlaxoSmithKline					Assay Description Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...				Bioorg Med Chem Lett 11: 2061-5 (2001) Article DOI: 10.1016/s0960-894x(01)00404-8 BindingDB Entry DOI: 10.7270/Q28P5XQG
					More data for this Ligand-Target Pair
Enoyl-ACP Reductase (FabI) (Staphylococcus aureus)	BDBM8748 (1-[(4-phenylphenyl)methyl]-4-(thiophen-3-yl)-1H-im...) Show SMILES C(c1ccc(cc1)-c1ccccc1)n1cnc(c1)-c1ccsc1 Show InChI InChI=1S/C20H16N2S/c1-2-4-17(5-3-1)18-8-6-16(7-9-18)12-22-13-20(21-15-22)19-10-11-23-14-19/h1-11,13-15H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.66E+3	n/a	n/a	n/a	n/a	6.5	30
GlaxoSmithKline					Assay Description Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...				Bioorg Med Chem Lett 11: 2061-5 (2001) Article DOI: 10.1016/s0960-894x(01)00404-8 BindingDB Entry DOI: 10.7270/Q28P5XQG
					More data for this Ligand-Target Pair