BDBM8762 1,2,3,4-Tetrahydropyrido[3,4-b]indole 7::4-({9-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl}carbonyl)phenol

SMILES: Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1

InChI Key: InChIKey=HULPDUSLVKXARL-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (FabI) (Escherichia coli)	BDBM8762 (1,2,3,4-Tetrahydropyrido[3,4-b]indole 7 | 4-({9-me...) Show SMILES Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C19H18N2O2/c1-20-17-5-3-2-4-15(17)16-10-11-21(12-18(16)20)19(23)13-6-8-14(22)9-7-13/h2-9,22H,10-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	30
GlaxoSmithKline					Assay Description Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...				Bioorg Med Chem Lett 11: 2241-4 (2001) Article DOI: 10.1016/s0960-894x(01)00405-x BindingDB Entry DOI: 10.7270/Q24X5610
					More data for this Ligand-Target Pair
Enoyl-ACP Reductase (FabI) (Staphylococcus aureus)	BDBM8762 (1,2,3,4-Tetrahydropyrido[3,4-b]indole 7 | 4-({9-me...) Show SMILES Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C19H18N2O2/c1-20-17-5-3-2-4-15(17)16-10-11-21(12-18(16)20)19(23)13-6-8-14(22)9-7-13/h2-9,22H,10-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	6.5	30
GlaxoSmithKline					Assay Description Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...				Bioorg Med Chem Lett 11: 2241-4 (2001) Article DOI: 10.1016/s0960-894x(01)00405-x BindingDB Entry DOI: 10.7270/Q24X5610
					More data for this Ligand-Target Pair