BDBM89825 2-(4-Fluoro-phenyl)-chromen-4-one::2-(4-fluorophenyl)-1-benzopyran-4-one::2-(4-fluorophenyl)chromen-4-one::2-(4-fluorophenyl)chromone::MLS000526645::SMR000117119::cid_261391

SMILES: Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key: InChIKey=ZHXIMGYEMBZGOI-UHFFFAOYSA-N

Data: 5 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 89825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM89825 (2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair
SKiNhead family member (skn-1) (Caenorhabditis elegans)	BDBM89825 (2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HH8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM89825 (2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay				J Med Chem 56: 3507-17 (2013) Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM89825 (2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human recombinant ARTD1 by fluorescence assay				J Med Chem 56: 3507-17 (2013) Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM89825 (2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...				J Med Chem 56: 3507-17 (2013) Article DOI: 10.1021/jm3018783 BindingDB Entry DOI: 10.7270/Q24M95W6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein HSP-16.2 (Caenorhabditis elegans)	BDBM89825 (2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C15H9FO2/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	>6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q21J98BN
					More data for this Ligand-Target Pair