BDBM91620 20q::alpha7 agonists 20q

SMILES: C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12

InChI Key: InChIKey=GCUWCNZGAUINME-NNZMDNLPSA-N

Data: 6 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 91620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholine Binding protein (Lymnaea stagnalis)	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	50	-9.79	n/a	n/a	n/a	n/a	n/a	7.4	20
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair
Acetylcholine Binding protein (Aplysia Californica)	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	120	-9.28	n/a	n/a	n/a	n/a	n/a	7.4	20
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair
Acetylcholine Binding protein (Aplysia Californica)	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	400	-8.58	n/a	n/a	n/a	n/a	n/a	7.4	20
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair
Acetylcholine Binding protein (Aplysia Californica)	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-8.34	n/a	n/a	n/a	n/a	n/a	7.4	20
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.50E+4	-6.84	n/a	n/a	n/a	n/a	n/a	7.4	37
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	>-6.41	n/a	n/a	n/a	n/a	n/a	7.4	37
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-7 subunit (Homo sapiens (Human))	BDBM91620 (20q | alpha7 agonists 20q) Show SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](C2)n1cc(nn1)C1(O)c2ccccc2-c2ccccc12 |THB:10:8:4.5:1| Show InChI InChI=1S/C24H27N4O/c1-28(2)17-11-12-18(28)14-16(13-17)27-15-23(25-26-27)24(29)21-9-5-3-7-19(21)20-8-4-6-10-22(20)24/h3-10,15-18,29H,11-14H2,1-2H3/q+1/t16-,17-,18+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	7.4	37
University of California, San Diego					Assay Description Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...				Taylor Research Group (2014) Article DOI: 10.1124/mol.112.080291 BindingDB Entry DOI: 10.7270/Q2805163
					More data for this Ligand-Target Pair