BDBM91698 Oxazolamine derivative, 5a

SMILES: Fc1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1

InChI Key: InChIKey=BWXLOGGHGYONLD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 91698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM91698 (Oxazolamine derivative, 5a) Show SMILES Fc1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 Show InChI InChI=1S/C23H17FN4O/c24-18-9-5-16(6-10-18)22(28-14-13-25-15-28)17-7-11-19(12-8-17)26-23-27-20-3-1-2-4-21(20)29-23/h1-15,22H,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a
Cardiff University					Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra...				J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5
					More data for this Ligand-Target Pair