BDBM91700 Oxazolamine derivative, 5c
SMILES: COC(=O)c1ccc(cc1)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1
InChI Key: InChIKey=XBGHZEQQURGHPO-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cytochrome CYP26A1 (Homo sapiens (Human)) | BDBM91700 (Oxazolamine derivative, 5c) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair |