Found 4 hits for monomerid = 91710 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441 BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441 BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 213 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441 BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 604 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441 BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this Ligand-Target Pair | |