BDBM92067 erk000492

SMILES: Cc1cnc(NC2CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=TUUNUSCSSOIZBW-GOSISDBHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM92067 (erk000492) Show SMILES Cc1cnc(NC2CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H22F3N5O2/c1-12-9-27-21(28-16-5-6-16)30-19(12)14-8-17(26-10-14)20(32)29-18(11-31)13-3-2-4-15(7-13)22(23,24)25/h2-4,7-10,16,18,26,31H,5-6,11H2,1H3,(H,29,32)(H,27,28,30)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	D3R	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description Photometric_Method2				D3R 222: (2015) BindingDB Entry DOI: 10.7270/Q2S46QSD
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM92067 (erk000492) Show SMILES Cc1cnc(NC2CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H22F3N5O2/c1-12-9-27-21(28-16-5-6-16)30-19(12)14-8-17(26-10-14)20(32)29-18(11-31)13-3-2-4-15(7-13)22(23,24)25/h2-4,7-10,16,18,26,31H,5-6,11H2,1H3,(H,29,32)(H,27,28,30)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSAR					Assay Description Assay 1 ...				CSAR 1: (2012)
					More data for this Ligand-Target Pair