BDBM92195 erk000653

SMILES: Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c(C)c1

InChI Key: InChIKey=NBXZVLHZQNHFDO-HSZRJFAPSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM92195 (erk000653) Show SMILES Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H27N5O2/c1-16-9-10-21(17(2)11-16)30-26-28-13-18(3)24(31-26)20-12-22(27-14-20)25(33)29-23(15-32)19-7-5-4-6-8-19/h4-14,23,27,32H,15H2,1-3H3,(H,29,33)(H,28,30,31)/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	D3R	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description Photometric_Method2				D3R 222: (2015) BindingDB Entry DOI: 10.7270/Q2S46QSD
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM92195 (erk000653) Show SMILES Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H27N5O2/c1-16-9-10-21(17(2)11-16)30-26-28-13-18(3)24(31-26)20-12-22(27-14-20)25(33)29-23(15-32)19-7-5-4-6-8-19/h4-14,23,27,32H,15H2,1-3H3,(H,29,33)(H,28,30,31)/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSAR					Assay Description Assay 1 ...				CSAR 1: (2012)
					More data for this Ligand-Target Pair