BDBM92370 RY Analogue, 10

SMILES: [#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(F)cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O

InChI Key: InChIKey=MANQNTALEMGDFM-HOTGVXAUSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AICAR transformylase (Homo sapiens (Human))	BDBM92370 (RY Analogue, 10) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(F)cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O |r| Show InChI InChI=1S/C19H29FN6O3/c1-3-23-17(28)16(11-13-6-8-14(20)9-7-13)26-18(29)15(25-12(2)27)5-4-10-24-19(21)22/h6-9,15-16H,3-5,10-11H2,1-2H3,(H,23,28)(H,25,27)(H,26,29)(H4,21,22,24)/t15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.35E+5	-5.28	n/a	n/a	n/a	n/a	n/a	n/a	25
University of Southampton					Assay Description Enzyme inhibition using aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).				Chembiochem 13: 1628-34 (2012) Article DOI: 10.1002/cbic.201200279 BindingDB Entry DOI: 10.7270/Q2P26WQZ
					More data for this Ligand-Target Pair