BDBM92463 Imipenem
SMILES: C[C@@H](O)[C@@H]1[C@H]2CC(SCCN=CN)[C@@H](N2C1=O)C(O)=O
InChI Key: InChIKey=KJHGPTOHUBEQPR-OCMJYRRLSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Acinetobacter baumannii) | BDBM92463 (Imipenem) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
York University | Assay Description Beta-lactam compounds were assessed as competitive inhibitors using nitrocefin as a reporter substrate. | J Biol Chem 286: 37292-303 (2011) Article DOI: 10.1074/jbc.M111.280115 BindingDB Entry DOI: 10.7270/Q2QV3K38 | |||||||||||
More data for this Ligand-Target Pair |