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BDBM92488 BI-92G11

SMILES: ONC(=O)CCS(=O)(=O)c1ccccc1

InChI Key: InChIKey=NUSZCZOBSDRJEK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92488   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-25


(Homo sapiens (Human))
BDBM92488
PNG
(BI-92G11)
Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)
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PC sid
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Article
PubMed
n/an/a 900n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)

More data for this
Ligand-Target Pair
Collagenase


(Homo sapiens (Human))
BDBM92488
PNG
(BI-92G11)
Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)

More data for this
Ligand-Target Pair
Collagenase


(homo sapiens (human))
BDBM92488
PNG
(BI-92G11)
Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)

More data for this
Ligand-Target Pair
Matrix metalloproteinase 14


(Homo sapiens (Human))
BDBM92488
PNG
(BI-92G11)
Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)
MMDB

Reactome pathway

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.09E+4n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)

More data for this
Ligand-Target Pair