BDBM92488 BI-92G11

SMILES: ONC(=O)CCS(=O)(=O)c1ccccc1

InChI Key: InChIKey=NUSZCZOBSDRJEK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-25 (Homo sapiens (Human))	BDBM92488 (BI-92G11) Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	37
Sanford-Burnham Medical Research Institute					Assay Description Inhibition of IC50 using matrix metalloproteinase.				J Biol Chem 285: 16076-86 (2010) Article DOI: 10.1074/jbc.M110.107094 BindingDB Entry DOI: 10.7270/Q2TM78QN
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM92488 (BI-92G11) Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	37
Sanford-Burnham Medical Research Institute					Assay Description Inhibition of IC50 using matrix metalloproteinase.				J Biol Chem 285: 16076-86 (2010) Article DOI: 10.1074/jbc.M110.107094 BindingDB Entry DOI: 10.7270/Q2TM78QN
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM92488 (BI-92G11) Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	37
Sanford-Burnham Medical Research Institute					Assay Description Inhibition of IC50 using matrix metalloproteinase.				J Biol Chem 285: 16076-86 (2010) Article DOI: 10.1074/jbc.M110.107094 BindingDB Entry DOI: 10.7270/Q2TM78QN
					More data for this Ligand-Target Pair
Matrix metalloproteinase 14 (Homo sapiens (Human))	BDBM92488 (BI-92G11) Show SMILES ONC(=O)CCS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C9H11NO4S/c11-9(10-12)6-7-15(13,14)8-4-2-1-3-5-8/h1-5,12H,6-7H2,(H,10,11)	MMDB Reactome pathway B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	37
Sanford-Burnham Medical Research Institute					Assay Description Inhibition of IC50 using matrix metalloproteinase.				J Biol Chem 285: 16076-86 (2010) Article DOI: 10.1074/jbc.M110.107094 BindingDB Entry DOI: 10.7270/Q2TM78QN
					More data for this Ligand-Target Pair