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BDBM92489 BI-102C8

SMILES: CCOc1ccc(cc1)-c1ccccc1C(=O)NO

InChI Key: InChIKey=SSQUTXCOTMRKGX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92489   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-25


(Homo sapiens (Human))
BDBM92489
PNG
(BI-102C8)
Show SMILES CCOc1ccc(cc1)-c1ccccc1C(=O)NO
Show InChI InChI=1S/C15H15NO3/c1-2-19-12-9-7-11(8-10-12)13-5-3-4-6-14(13)15(17)16-18/h3-10,18H,2H2,1H3,(H,16,17)
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n/an/a 2.50E+3n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)


Article DOI: 10.1074/jbc.M110.107094
More data for this
Ligand-Target Pair
Collagenase


(Homo sapiens (Human))
BDBM92489
PNG
(BI-102C8)
Show SMILES CCOc1ccc(cc1)-c1ccccc1C(=O)NO
Show InChI InChI=1S/C15H15NO3/c1-2-19-12-9-7-11(8-10-12)13-5-3-4-6-14(13)15(17)16-18/h3-10,18H,2H2,1H3,(H,16,17)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)


Article DOI: 10.1074/jbc.M110.107094
More data for this
Ligand-Target Pair
Collagenase


(Homo sapiens (Human))
BDBM92489
PNG
(BI-102C8)
Show SMILES CCOc1ccc(cc1)-c1ccccc1C(=O)NO
Show InChI InChI=1S/C15H15NO3/c1-2-19-12-9-7-11(8-10-12)13-5-3-4-6-14(13)15(17)16-18/h3-10,18H,2H2,1H3,(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)


Article DOI: 10.1074/jbc.M110.107094
More data for this
Ligand-Target Pair
Matrix metalloproteinase 14


(Homo sapiens (Human))
BDBM92489
PNG
(BI-102C8)
Show SMILES CCOc1ccc(cc1)-c1ccccc1C(=O)NO
Show InChI InChI=1S/C15H15NO3/c1-2-19-12-9-7-11(8-10-12)13-5-3-4-6-14(13)15(17)16-18/h3-10,18H,2H2,1H3,(H,16,17)
MMDB

Reactome pathway

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/a37



Sanford-Burnham Medical Research Institute



Assay Description
Inhibition of IC50 using matrix metalloproteinase.


J Biol Chem 285: 16076-86 (2010)


Article DOI: 10.1074/jbc.M110.107094
More data for this
Ligand-Target Pair