BDBM92495 Malate
SMILES: OC(CC(O)=O)C(O)=O
InChI Key: InChIKey=BJEPYKJPYRNKOW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human)) | BDBM92495 (Malate) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in... | J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methyl-accepting chemotaxis protein (McpS) (Pseudomonas putida (Arthrobacter siderocapsulatus)) | BDBM92495 (Malate) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | 20 |
CSIC | Assay Description Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA). | J Biol Chem 285: 23126-36 (2010) Article DOI: 10.1074/jbc.M110.110403 BindingDB Entry DOI: 10.7270/Q2K64GNS | |||||||||||
More data for this Ligand-Target Pair |
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kcal/mole | -TΔS° kcal/mole | ΔH° kcal/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
Methyl-accepting chemotaxis protein (McpS) (Pseudomonas putida (Arthrobacter siderocapsulatus)) | BDBM92495 (Malate) | GoogleScholar | CHEBI KEGG MMDB PC cid PC sid | -6.80 | 16.1 | -22.9 | 5.07 | n/a | 20 | |
CSIC | J Biol Chem 285: 23126-36 (2010) |