BDBM92597 CHEMBL324501::NAD Synthetase Inhibitor, 2
SMILES: C[N+](C)(C)c1ccc(CC(=O)OCCCCCCCCn2ccc3cc(OCc4ccccc4)ccc23)cc1
InChI Key: InChIKey=XBRRCRBXGRSKKD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NH(3)-dependent NAD(+) synthetase (Bacillus subtilis) | BDBM92597 (CHEMBL324501 | NAD Synthetase Inhibitor, 2) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alabama at Birmingham Curated by ChEMBL | Assay Description Inhibitory activity against Bacillus subtilis NAD synthetase | J Med Chem 46: 3371-81 (2003) Article DOI: 10.1021/jm030003x BindingDB Entry DOI: 10.7270/Q25T3M6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD synthetase (Homo sapiens (Human)) | BDBM92597 (CHEMBL324501 | NAD Synthetase Inhibitor, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.48E+4 | n/a | n/a | n/a | n/a | 8.5 | 37 |
National Institutes of Health | Assay Description Inhibition assay using NAD synthetase. | J Biol Chem 283: 19329-41 (2008) Article DOI: 10.1074/jbc.M800694200 BindingDB Entry DOI: 10.7270/Q27P8X0W | |||||||||||
More data for this Ligand-Target Pair |