BDBM92598 NAD Synthetase Inhibitor, 3
SMILES: COC(=O)c1cc2cc(OCc3ccccc3)ccc2n1CCCCCCCOC(=O)Cc1ccc[n+](C)c1
InChI Key: InChIKey=XQIQVUZCEKJPNU-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD synthetase (Homo sapiens (Human)) | BDBM92598 (NAD Synthetase Inhibitor, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.33E+4 | n/a | n/a | n/a | n/a | 8.5 | 37 |
National Institutes of Health | Assay Description Inhibition assay using NAD synthetase. | J Biol Chem 283: 19329-41 (2008) Article DOI: 10.1074/jbc.M800694200 BindingDB Entry DOI: 10.7270/Q27P8X0W | |||||||||||
More data for this Ligand-Target Pair |