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BDBM92616 Difluoroketone phospholipid analogue, 4

SMILES: CCCCCCCC(=O)OCC(COP([O-])(=O)OCC[N+](C)(C)C)CC(=O)C(F)(F)CCCCCC

InChI Key: InChIKey=RDVQEKAXYPFFSQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92616   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lecithin-cholesterol acyltransferase (LCAT)


(Homo sapiens (Human))		BDBM92616
PNG
(Difluoroketone phospholipid analogue, 4)
Show SMILES CCCCCCCC(=O)OCC(COP([O-])(=O)OCC[N+](C)(C)C)CC(=O)C(F)(F)CCCCCC
Show InChI InChI=1S/C25H48F2NO7P/c1-6-8-10-12-13-15-24(30)33-20-22(19-23(29)25(26,27)16-14-11-9-7-2)21-35-36(31,32)34-18-17-28(3,4)5/h22H,6-21H2,1-5H3
PDB

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PC cid
PC sid
UniChem
n/an/a 60n/an/an/an/a7.54



Dalhousie University



Assay Description
The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...

J Biol Chem 264: 1963-1967 (1989)


BindingDB Entry DOI: 10.7270/Q2M0441T
More data for this
Ligand-Target Pair