BDBM92633 Thiazolidine-dione, 2

SMILES: CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C

InChI Key: InChIKey=MGXJFHQMSHIMIV-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM92633 (Thiazolidine-dione, 2) Show SMILES CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C |w:12.12,5.5| Show InChI InChI=1S/C12H14N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17H,1,3,5H2,2,4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd.					Assay Description Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.				J Biol Chem 265: 22255-61 (1990) BindingDB Entry DOI: 10.7270/Q2319TGH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM92633 (Thiazolidine-dione, 2) Show SMILES CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C |w:12.12,5.5| Show InChI InChI=1S/C12H14N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17H,1,3,5H2,2,4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd.					Assay Description Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.				J Biol Chem 265: 22255-61 (1990) BindingDB Entry DOI: 10.7270/Q2319TGH
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human))	BDBM92633 (Thiazolidine-dione, 2) Show SMILES CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C |w:12.12,5.5| Show InChI InChI=1S/C12H14N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17H,1,3,5H2,2,4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd.					Assay Description Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.				J Biol Chem 265: 22255-61 (1990) BindingDB Entry DOI: 10.7270/Q2319TGH
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM92633 (Thiazolidine-dione, 2) Show SMILES CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C |w:12.12,5.5| Show InChI InChI=1S/C12H14N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17H,1,3,5H2,2,4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd.					Assay Description Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.				J Biol Chem 265: 22255-61 (1990) BindingDB Entry DOI: 10.7270/Q2319TGH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase CSK (Homo sapiens (Human))	BDBM92633 (Thiazolidine-dione, 2) Show SMILES CC(=C)CN1C(SC(=C)C1=O)=NN=c1scc(O)n1C |w:12.12,5.5| Show InChI InChI=1S/C12H14N4O2S2/c1-7(2)5-16-10(18)8(3)20-12(16)14-13-11-15(4)9(17)6-19-11/h6,17H,1,3,5H2,2,4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd.					Assay Description Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.				J Biol Chem 265: 22255-61 (1990) BindingDB Entry DOI: 10.7270/Q2319TGH
					More data for this Ligand-Target Pair