BDBM92761 PDF inhibitor, compound 3
SMILES: CNC(=O)[C@@H]1CSCN1c1nc(Nc2c(C)cccc2C(=O)NC)nc(n1)N1CCN(CC1)c1ccccc1Cl
InChI Key: InChIKey=QRGGVLXBPSQEDF-NRFANRHFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Peptide deformylase (Streptococcus pneumoniae (strain ATCC BAA-255 / R6...) | BDBM92761 (PDF inhibitor, compound 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 117 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline | Assay Description Binding assay using PDF inhibitors. | Biochemistry 50: 6642-54 (2011) Article DOI: 10.1021/bi200655g BindingDB Entry DOI: 10.7270/Q2MS3RBV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |