BDBM92818 Bisanilinopyrimidine, 6k

SMILES: OC(=O)c1ccc(Nc2nccc(Nc3ccccc3Cl)n2)c(O)c1

InChI Key: InChIKey=KIRMRPKSCCDONI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM92818 (Bisanilinopyrimidine, 6k) Show SMILES OC(=O)c1ccc(Nc2nccc(Nc3ccccc3Cl)n2)c(O)c1 Show InChI InChI=1S/C17H13ClN4O3/c18-11-3-1-2-4-12(11)20-15-7-8-19-17(22-15)21-13-6-5-10(16(24)25)9-14(13)23/h1-9,23H,(H,24,25)(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Moffitt Cancer Center					Assay Description In vitro enzyme activity assay using Aurora Kinase A.				J Med Chem 55: 7392-416 (2012) Article DOI: 10.1021/jm300334d BindingDB Entry DOI: 10.7270/Q2V986NH
					More data for this Ligand-Target Pair