BDBM92851 Nicotinamidase Inhibitor, 18

SMILES: COc1cncc(C=O)c1

InChI Key: InChIKey=YOVIXSRXKCZJRN-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamidase (SpNic) (Streptococcus pneumoniae)	BDBM92851 (Nicotinamidase Inhibitor, 18) Show SMILES COc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Nicotinamidase (CePNC2) (Caenorhabditis elegans)	BDBM92851 (Nicotinamidase Inhibitor, 18) Show SMILES COc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Nicotinamidase (CePNC1) (Caenorhabditis elegans)	BDBM92851 (Nicotinamidase Inhibitor, 18) Show SMILES COc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Nicotinamidase (BbNic) (Borrelia burgdorferi)	BDBM92851 (Nicotinamidase Inhibitor, 18) Show SMILES COc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair
Nicotinamidase (Pnc1) (Saccharomyces cerevisiae)	BDBM92851 (Nicotinamidase Inhibitor, 18) Show SMILES COc1cncc(C=O)c1 Show InChI InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University					Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen...				Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC
					More data for this Ligand-Target Pair