BDBM92856 Nicotinamidase Inhibitor, 23::PncA Inhibitor, 5
SMILES: N#Cc1cccnc1
InChI Key: InChIKey=GZPHSAQLYPIAIN-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotinamidase (Pnc1) (Saccharomyces cerevisiae) | BDBM92856 (Nicotinamidase Inhibitor, 23 | PncA Inhibitor, 5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cornell University | Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen... | Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinamidase (PncA) (Mycobacterium tuberculosis) | BDBM92856 (Nicotinamidase Inhibitor, 23 | PncA Inhibitor, 5) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine | Assay Description Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a... | Biochemistry 49: 9613-9 (2010) Article DOI: 10.1021/bi1011157 BindingDB Entry DOI: 10.7270/Q2BC3X52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinamidase (SpNic) (Streptococcus pneumoniae) | BDBM92856 (Nicotinamidase Inhibitor, 23 | PncA Inhibitor, 5) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cornell University | Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen... | Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nicotinamidase (BbNic) (Borrelia burgdorferi) | BDBM92856 (Nicotinamidase Inhibitor, 23 | PncA Inhibitor, 5) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cornell University | Assay Description Nicotinamidase activity was monitored by coupling the production of ammonia with the consumption of NAD(P)H by the enzyme bovine glutamate dehydrogen... | Biochemistry 49: 10421-39 (2010) Article DOI: 10.1021/bi1012518 BindingDB Entry DOI: 10.7270/Q2G44NWC | |||||||||||
More data for this Ligand-Target Pair |