BindingDB PrimarySearch

null

SMILES: Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1

InChI Key: InChIKey=JOGKUKXHTYWRGZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 140 hits for monomerid = 92862
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin)				Bioorg Med Chem 26: 4537-4543 (2018) Article DOI: 10.1016/j.bmc.2018.07.047 BindingDB Entry DOI: 10.7270/Q20C4ZDW
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin)				Bioorg Med Chem 26: 4537-4543 (2018) Article DOI: 10.1016/j.bmc.2018.07.047 BindingDB Entry DOI: 10.7270/Q20C4ZDW
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin)				Bioorg Med Chem 26: 4537-4543 (2018) Article DOI: 10.1016/j.bmc.2018.07.047 BindingDB Entry DOI: 10.7270/Q20C4ZDW
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal His-tagged PI3K p110delta/p85alpha using lipid substrate after 60 mins by ADP-Glo assay				Bioorg Med Chem 26: 4537-4543 (2018) Article DOI: 10.1016/j.bmc.2018.07.047 BindingDB Entry DOI: 10.7270/Q20C4ZDW
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin)				Bioorg Med Chem 26: 4537-4543 (2018) Article DOI: 10.1016/j.bmc.2018.07.047 BindingDB Entry DOI: 10.7270/Q20C4ZDW
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				Bioorg Med Chem 26: 4537-4543 (2018) Article DOI: 10.1016/j.bmc.2018.07.047 BindingDB Entry DOI: 10.7270/Q20C4ZDW
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human PI3K-beta using PIP2:3PS as substrate preincubated for 15 mins followed by ATP addition measured after 1 hr by ADP-Gl...				Bioorg Med Chem 26: 3982-3991 (2018) Article DOI: 10.1016/j.bmc.2018.06.022 BindingDB Entry DOI: 10.7270/Q2FR0098
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human PI3K-gamma using PIP2:3PS as substrate preincubated for 15 mins followed by ATP addition measured after 1 hr by ADP-G...				Bioorg Med Chem 26: 3982-3991 (2018) Article DOI: 10.1016/j.bmc.2018.06.022 BindingDB Entry DOI: 10.7270/Q2FR0098
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human PI3K-delta using PIP2:3PS as substrate preincubated for 15 mins followed by ATP addition measured after 1 hr by ADP-G...				Bioorg Med Chem 26: 3982-3991 (2018) Article DOI: 10.1016/j.bmc.2018.06.022 BindingDB Entry DOI: 10.7270/Q2FR0098
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human PI3K-alpha using PIP2:3PS as substrate preincubated for 15 mins followed by ATP addition measured after 1 hr by ADP-G...				Bioorg Med Chem 26: 3982-3991 (2018) Article DOI: 10.1016/j.bmc.2018.06.022 BindingDB Entry DOI: 10.7270/Q2FR0098
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr by Kinase-Glo luminescent assay				Bioorg Med Chem 26: 3992-4000 (2018) Article DOI: 10.1016/j.bmc.2018.06.025 BindingDB Entry DOI: 10.7270/Q2668GVK
Nanjing University of Chinese Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3K p110gamma (unknown origin) using PIP2 as substrate by ELISA				Eur J Med Chem 146: 460-470 (2018) Article DOI: 10.1016/j.ejmech.2018.01.081 BindingDB Entry DOI: 10.7270/Q2NZ8B7G
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3K p110alpha (unknown origin) using PIP2 as substrate by ELISA				Eur J Med Chem 146: 460-470 (2018) Article DOI: 10.1016/j.ejmech.2018.01.081 BindingDB Entry DOI: 10.7270/Q2NZ8B7G
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3K p110delta (unknown origin) using PIP2 as substrate by ELISA				Eur J Med Chem 146: 460-470 (2018) Article DOI: 10.1016/j.ejmech.2018.01.081 BindingDB Entry DOI: 10.7270/Q2NZ8B7G
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PI3K p110beta (unknown origin) using PIP2 as substrate by ELISA				Eur J Med Chem 146: 460-470 (2018) Article DOI: 10.1016/j.ejmech.2018.01.081 BindingDB Entry DOI: 10.7270/Q2NZ8B7G
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged full length PI3K p120gamma expressed in baculovirus infected Sf21 insect cells by ELISA				Bioorg Med Chem 26: 1675-1685 (2018) Article DOI: 10.1016/j.bmc.2018.02.015 BindingDB Entry DOI: 10.7270/Q2GF0X3Z
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged recombinant full-length PI3Kbeta (unknown origin)/untagged recombinant full length p85alpha expressed in baculov...				Bioorg Med Chem 26: 1675-1685 (2018) Article DOI: 10.1016/j.bmc.2018.02.015 BindingDB Entry DOI: 10.7270/Q2GF0X3Z
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal His6-tagged full length PI3K p110alpha (unknown origin)/recombinant untagged full length p85alpha (unknown origi...				Bioorg Med Chem 26: 1675-1685 (2018) Article DOI: 10.1016/j.bmc.2018.02.015 BindingDB Entry DOI: 10.7270/Q2GF0X3Z
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal full length human PI3K p110delta/recombinant untagged full length human p85alpha expressed in baculovirus infect...				Bioorg Med Chem 26: 1675-1685 (2018) Article DOI: 10.1016/j.bmc.2018.02.015 BindingDB Entry DOI: 10.7270/Q2GF0X3Z
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3K-beta (unknown origin) after 40 mins by Kinase-Glo assay				Eur J Med Chem 157: 37-49 (2018) Article DOI: 10.1016/j.ejmech.2018.07.061 BindingDB Entry DOI: 10.7270/Q2ZC85KT
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of recombinant full length PI3K p110alpha/p85alpha (unknown origin) expressed in baculovirus infected sf9 cells using PIP2 as substrate pr...				Eur J Med Chem 157: 37-49 (2018) Article DOI: 10.1016/j.ejmech.2018.07.061 BindingDB Entry DOI: 10.7270/Q2ZC85KT
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3K-gamma (unknown origin) after 40 mins by Kinase-Glo assay				Eur J Med Chem 157: 37-49 (2018) Article DOI: 10.1016/j.ejmech.2018.07.061 BindingDB Entry DOI: 10.7270/Q2ZC85KT
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3K-delta (unknown origin) after 40 mins by Kinase-Glo assay				Eur J Med Chem 157: 37-49 (2018) Article DOI: 10.1016/j.ejmech.2018.07.061 BindingDB Entry DOI: 10.7270/Q2ZC85KT
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assay				Eur J Med Chem 158: 707-719 (2018) Article DOI: 10.1016/j.ejmech.2018.09.002 BindingDB Entry DOI: 10.7270/Q2PK0JVH
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of wild type PI3Kalpha (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assay				Eur J Med Chem 158: 707-719 (2018) Article DOI: 10.1016/j.ejmech.2018.09.002 BindingDB Entry DOI: 10.7270/Q2PK0JVH
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assay				Eur J Med Chem 158: 707-719 (2018) Article DOI: 10.1016/j.ejmech.2018.09.002 BindingDB Entry DOI: 10.7270/Q2PK0JVH
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assay				Eur J Med Chem 158: 707-719 (2018) Article DOI: 10.1016/j.ejmech.2018.09.002 BindingDB Entry DOI: 10.7270/Q2PK0JVH
Chongqing University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assay				Bioorg Med Chem 23: 7585-96 (2015) Article DOI: 10.1016/j.bmc.2015.11.003 BindingDB Entry DOI: 10.7270/Q2HD7ZPM
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	421	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of PI3K beta (unknown origin) using lipid substrate measured after 40 mins in presence of ATP by Kinase-Glo plus reagent based luminescenc...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.05.043 BindingDB Entry DOI: 10.7270/Q2833W8M
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of PI3K delta (unknown origin) using lipid substrate measured after 40 mins in presence of ATP by Kinase-Glo plus reagent based luminescen...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.05.043 BindingDB Entry DOI: 10.7270/Q2833W8M
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of PI3K gamma (unknown origin) using lipid substrate measured after 40 mins in presence of ATP by Kinase-Glo plus reagent based luminescen...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.05.043 BindingDB Entry DOI: 10.7270/Q2833W8M
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hr				Bioorg Med Chem Lett 29: 1313-1319 (2019) Article DOI: 10.1016/j.bmcl.2019.04.007 BindingDB Entry DOI: 10.7270/Q2TM7FJG
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hr				Bioorg Med Chem Lett 29: 1313-1319 (2019) Article DOI: 10.1016/j.bmcl.2019.04.007 BindingDB Entry DOI: 10.7270/Q2TM7FJG
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylation				Bioorg Med Chem Lett 29: 1313-1319 (2019) Article DOI: 10.1016/j.bmcl.2019.04.007 BindingDB Entry DOI: 10.7270/Q2TM7FJG
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hr				Bioorg Med Chem Lett 29: 1313-1319 (2019) Article DOI: 10.1016/j.bmcl.2019.04.007 BindingDB Entry DOI: 10.7270/Q2TM7FJG
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hr				Bioorg Med Chem Lett 29: 1313-1319 (2019) Article DOI: 10.1016/j.bmcl.2019.04.007 BindingDB Entry DOI: 10.7270/Q2TM7FJG
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
West China Hospital of Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged PI3Kalpha (1 to 1068 residues)/PIK3R1 (1 to 724 residues) expressed in baculovirus ...				Eur J Med Chem 178: 667-686 (2019) Article DOI: 10.1016/j.ejmech.2019.06.021 BindingDB Entry DOI: 10.7270/Q2KH0RP4
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
West China Hospital of Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged PI3Kdelta (1 to 1044 residues)/PIK3R1 (1 to 724 residues) expressed in baculovirus ...				Eur J Med Chem 178: 667-686 (2019) Article DOI: 10.1016/j.ejmech.2019.06.021 BindingDB Entry DOI: 10.7270/Q2KH0RP4
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
West China Hospital of Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal DYKDDDDK-tagged PI3Kgamma (1 to 1102 residues) expressed in baculovirus expression system usin...				Eur J Med Chem 178: 667-686 (2019) Article DOI: 10.1016/j.ejmech.2019.06.021 BindingDB Entry DOI: 10.7270/Q2KH0RP4
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	704	n/a	n/a	n/a	n/a	n/a	n/a
West China Hospital of Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged PI3Kbeta (1 to 1070 residues)/PIK3R1 (1 to 724 residues) expressed in baculovirus e...				Eur J Med Chem 178: 667-686 (2019) Article DOI: 10.1016/j.ejmech.2019.06.021 BindingDB Entry DOI: 10.7270/Q2KH0RP4
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
West China Hospital of Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) using Ulight-4E-BP1 as substrate incubated for 30 mins by fluoresc...				Eur J Med Chem 178: 667-686 (2019) Article DOI: 10.1016/j.ejmech.2019.06.021 BindingDB Entry DOI: 10.7270/Q2KH0RP4
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
School of Traditional Chinese Pharmacy Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111630 BindingDB Entry DOI: 10.7270/Q2W380Q5
School of Traditional Chinese Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
School of Traditional Chinese Pharmacy Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111630 BindingDB Entry DOI: 10.7270/Q2W380Q5
School of Traditional Chinese Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
School of Traditional Chinese Pharmacy Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111630 BindingDB Entry DOI: 10.7270/Q2W380Q5
School of Traditional Chinese Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
School of Traditional Chinese Pharmacy Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111630 BindingDB Entry DOI: 10.7270/Q2W380Q5
School of Traditional Chinese Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
School of Traditional Chinese Pharmacy Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin)				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111630 BindingDB Entry DOI: 10.7270/Q2W380Q5
School of Traditional Chinese Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assay				Bioorg Med Chem Lett 26: 4408-4413 (2016) Article DOI: 10.1016/j.bmcl.2016.08.015 BindingDB Entry DOI: 10.7270/Q23R0XDP
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assay				Bioorg Med Chem Lett 26: 4408-4413 (2016) Article DOI: 10.1016/j.bmcl.2016.08.015 BindingDB Entry DOI: 10.7270/Q23R0XDP
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM92862 (US9284315, BEZ-235 \| mTOR Inhibitor, BEZ235) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	421	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) assessed as reduction in ATP depletion using lipid substrate after 40 mins by Kinase-Glo luminescent assay				Bioorg Med Chem Lett 26: 4408-4413 (2016) Article DOI: 10.1016/j.bmcl.2016.08.015 BindingDB Entry DOI: 10.7270/Q23R0XDP
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair

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