BDBM92872 4-Aminoquinazoline derivative, 6g

SMILES: CCOC(=O)c1csc2cc(Nc3ncnc4cc(OCCCN5CCCCC5)ccc34)ccc12

InChI Key: InChIKey=DKPKQIUVTWRWMA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM92872 (4-Aminoquinazoline derivative, 6g) Show SMILES CCOC(=O)c1csc2cc(Nc3ncnc4cc(OCCCN5CCCCC5)ccc34)ccc12 Show InChI InChI=1S/C27H30N4O3S/c1-2-33-27(32)23-17-35-25-15-19(7-9-21(23)25)30-26-22-10-8-20(16-24(22)28-18-29-26)34-14-6-13-31-11-4-3-5-12-31/h7-10,15-18H,2-6,11-14H2,1H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	822	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University					Assay Description The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.				Chem Biol Drug Des 81: 399-407 (2013) Article DOI: 10.1111/cbdd.12089 BindingDB Entry DOI: 10.7270/Q2Z31X71
					More data for this Ligand-Target Pair