BDBM92892 NS3 Protease Inhibitor, 3
SMILES: OC(=O)CC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)CCC(O)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CS)C(O)=O
InChI Key: InChIKey=VNSGNUMKGWKSSC-STFWXSJUSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NS3 protein (Hepatitis C virus) | BDBM92892 (NS3 Protease Inhibitor, 3) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University | Assay Description Analysis of the inhibition activation of flNS3 by the inhibitors was performed with the standard assay, allowing the inhibitor to preincubate with NS... | Biochemistry 48: 11592-602 (2009) Article DOI: 10.1021/bi9016928 BindingDB Entry DOI: 10.7270/Q2F47MR0 | |||||||||||
More data for this Ligand-Target Pair |