BDBM92918 Benzofuranone, 7
SMILES: COc1ccc2OC(=O)C3(CC(C)c4ccccc34)c2c1
InChI Key: InChIKey=GOWNABBGKSIXRG-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM92918 (Benzofuranone, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.10E+4 | -5.95 | n/a | n/a | n/a | n/a | n/a | 7.8 | 5 |
Max Planck Research | Assay Description PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v... | Biochemistry 48: 6268-77 (2009) Article DOI: 10.1021/bi9007287 BindingDB Entry DOI: 10.7270/Q2X34W26 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclophilin B (CypB) (Homo sapiens (Human)) | BDBM92918 (Benzofuranone, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+5 | >-5.09 | n/a | n/a | n/a | n/a | n/a | 7.8 | 5 |
Max Planck Research | Assay Description PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v... | Biochemistry 48: 6268-77 (2009) Article DOI: 10.1021/bi9007287 BindingDB Entry DOI: 10.7270/Q2X34W26 | |||||||||||
More data for this Ligand-Target Pair |