BDBM93041 Shinanolone
SMILES: C[C@@H]1CC(=O)c2c(O)cccc2[C@@H]1O
InChI Key: InChIKey=YUPNHTWYVBHLMG-KSBSHMNSSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit A (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM93041 (Shinanolone) | PDB MMDB B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
John Innes Centre | Assay Description Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously. | J Biol Chem 288: 5149-56 (2013) Article DOI: 10.1074/jbc.M112.419069 BindingDB Entry DOI: 10.7270/Q2V69H6R | |||||||||||
More data for this Ligand-Target Pair |