BDBM93051 TLM analog, 8
SMILES: COC(=O)C1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O
InChI Key: InChIKey=HVZBKCZSQRQCCD-UPHFVGOQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-ketoacyl-ACP synthase (KasA) C171Q (Mycobacterium tuberculosis) | BDBM93051 (TLM analog, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery | Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... | J Biol Chem 288: 6045-52 (2013) Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-ketoacyl-ACP synthase (KasA) (Mycobacterium tuberculosis) | BDBM93051 (TLM analog, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.14E+4 | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery | Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... | J Biol Chem 288: 6045-52 (2013) Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 | |||||||||||
More data for this Ligand-Target Pair |