BDBM93204 Mercaptomethyl ketone Inhibitor, 53
SMILES: NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)CSCC(O)=O
InChI Key: InChIKey=LULWFYHYSZTYKF-VXKWHMMOSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin B (Homo sapiens (Human)) | BDBM93204 (Mercaptomethyl ketone Inhibitor, 53) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | 5.5 | n/a |
University of California-Berkeley | Assay Description A fluorometric high-throughput assay for activity against cathepsin B was performed in 96-well microtiter plates. The assay were performed in Dynate... | J Comb Chem 5: 869-80 (2003) Article DOI: 10.1021/cc034008r BindingDB Entry DOI: 10.7270/Q28914GH | |||||||||||
More data for this Ligand-Target Pair |