BDBM93407 MAP Kinase Inhibitor, 11

SMILES: Clc1ccc(cc1Cl)-c1cc([nH]c(=O)c1C#N)-c1ccc(Br)cc1

InChI Key: InChIKey=LETZLGFBMSOKTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 93407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM93407 (MAP Kinase Inhibitor, 11) Show SMILES Clc1ccc(cc1Cl)-c1cc([nH]c(=O)c1C#N)-c1ccc(Br)cc1 Show InChI InChI=1S/C18H9BrCl2N2O/c19-12-4-1-10(2-5-12)17-8-13(14(9-22)18(24)23-17)11-3-6-15(20)16(21)7-11/h1-8H,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.5	37
German University in Cairo					Assay Description Kinase assay using p38alpha MAP.				J Comb Chem 12: 559-65 (2010) Article DOI: 10.1021/cc1000488 BindingDB Entry DOI: 10.7270/Q2FT8JN3
					More data for this Ligand-Target Pair