BDBM97666 US8476295, 1.1.04
SMILES: Cc1ccc(CN2C3CCC2CC(C3)Nc2ccc3[nH]ncc3c2)cc1OCCO
InChI Key: InChIKey=ODUYVHAFJTXMAF-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho kinase 2 (ROCKII) (Homo sapiens (Human)) | BDBM97666 (US8476295, 1.1.04) | PDB MMDB B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (ROCK1) (Homo Sapiens (Human)) | BDBM97666 (US8476295, 1.1.04) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 35 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Inspire US Patent | Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). | US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS | |||||||||||
More data for this Ligand-Target Pair |