BDBM97668 US8476295, 3.1.01

SMILES: C(N1CC2CCC1C2Nc1ccc2[nH]ncc2c1)c1ccccc1

InChI Key: InChIKey=UTVPCECSRXIEDH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho kinase 2 (ROCKII) (Homo sapiens (Human))	BDBM97668 (US8476295, 3.1.01) Show SMILES C(N1CC2CCC1C2Nc1ccc2[nH]ncc2c1)c1ccccc1 |TLB:0:1:5.4:7,8:7:1.2:5.4| Show InChI InChI=1S/C20H22N4/c1-2-4-14(5-3-1)12-24-13-15-6-9-19(24)20(15)22-17-7-8-18-16(10-17)11-21-23-18/h1-5,7-8,10-11,15,19-20,22H,6,9,12-13H2,(H,21,23)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	464	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Inspire US Patent					Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).				US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (ROCK1) (Homo Sapiens (Human))	BDBM97668 (US8476295, 3.1.01) Show SMILES C(N1CC2CCC1C2Nc1ccc2[nH]ncc2c1)c1ccccc1 |TLB:0:1:5.4:7,8:7:1.2:5.4| Show InChI InChI=1S/C20H22N4/c1-2-4-14(5-3-1)12-24-13-15-6-9-19(24)20(15)22-17-7-8-18-16(10-17)11-21-23-18/h1-5,7-8,10-11,15,19-20,22H,6,9,12-13H2,(H,21,23)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	976	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Inspire US Patent					Assay Description Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).				US Patent US8476295 (2013) BindingDB Entry DOI: 10.7270/Q2H993TS
					More data for this Ligand-Target Pair