BDBM97730 US8481564, 6

SMILES: OCc1cc(NC(=O)c2nc(c[nH]2)C#N)c(cc1C1CNS(=O)(=O)NC1)C1=CCCCC1

InChI Key: InChIKey=ZRWFZYJQPSPUJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 (CSF-1) (Mus musculus (Mouse))	BDBM97730 (US8481564, 6) Show SMILES OCc1cc(NC(=O)c2nc(c[nH]2)C#N)c(cc1C1CNS(=O)(=O)NC1)C1=CCCCC1 |t:29| Show InChI InChI=1S/C21H24N6O4S/c22-8-16-11-23-20(26-16)21(29)27-19-6-14(12-28)17(15-9-24-32(30,31)25-10-15)7-18(19)13-4-2-1-3-5-13/h4,6-7,11,15,24-25,28H,1-3,5,9-10,12H2,(H,23,26)(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...				US Patent US8481564 (2013) BindingDB Entry DOI: 10.7270/Q2QV3K4Q
					More data for this Ligand-Target Pair