BDBM97733 US8481564, 9

SMILES: CN1CC(CN(C)C1=O)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCCC1

InChI Key: InChIKey=MHYHMWPNTWEFCB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 (CSF-1) (Mus musculus (Mouse))	BDBM97733 (US8481564, 9) Show SMILES CN1CC(CN(C)C1=O)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCCC1 |t:28| Show InChI InChI=1S/C24H28N6O2/c1-29-14-18(15-30(2)24(29)32)17-9-10-21(20(11-17)16-7-5-3-4-6-8-16)28-23(31)22-26-13-19(12-25)27-22/h7,9-11,13,18H,3-6,8,14-15H2,1-2H3,(H,26,27)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...				US Patent US8481564 (2013) BindingDB Entry DOI: 10.7270/Q2QV3K4Q
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