BDBM97763 US8476225, 24

SMILES: CC(C)(C)[C@H](NC(=O)OC1CCCC1)C(=O)N1CN(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)S(=O)(=O)c1ccsc1

InChI Key: InChIKey=IVCDQOUQYLNEJW-SJWLOSKGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-1657] (Hepatitis C virus genotype 1a (isolate 1) (HCV))	BDBM97763 (US8476225, 24) Show SMILES CC(C)(C)[C@H](NC(=O)OC1CCCC1)C(=O)N1CN(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)S(=O)(=O)c1ccsc1 |r| Show InChI InChI=1S/C29H41N5O9S3/c1-5-18-14-29(18,26(37)32-45(39,40)20-10-11-20)31-24(35)22-15-33(46(41,42)21-12-13-44-16-21)17-34(22)25(36)23(28(2,3)4)30-27(38)43-19-8-6-7-9-19/h5,12-13,16,18-20,22-23H,1,6-11,14-15,17H2,2-4H3,(H,30,38)(H,31,35)(H,32,37)/t18-,22+,23-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	37
Gilead Sciences, Inc. US Patent					Assay Description Inhibition assay using HCV protease.				US Patent US8476225 (2013) BindingDB Entry DOI: 10.7270/Q2M32TD9
					More data for this Ligand-Target Pair