BDBM97773 US8476225, 34

SMILES: CC(C)(C)[C@H](NC(=O)OC1CCCC1)C(=O)N1CN(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=FNPPNXHVVMWPBT-MQHVEIOXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-1657] (Hepatitis C virus genotype 1a (isolate 1) (HCV))	BDBM97773 (US8476225, 34) Show SMILES CC(C)(C)[C@H](NC(=O)OC1CCCC1)C(=O)N1CN(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C37H47N5O7S/c1-5-26-21-37(26,34(45)40-50(47,48)29-19-20-29)39-32(43)30-22-41(27-17-15-25(16-18-27)24-11-7-6-8-12-24)23-42(30)33(44)31(36(2,3)4)38-35(46)49-28-13-9-10-14-28/h5-8,11-12,15-18,26,28-31H,1,9-10,13-14,19-23H2,2-4H3,(H,38,46)(H,39,43)(H,40,45)/t26-,30+,31-,37-/m1/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	37
Gilead Sciences, Inc. US Patent					Assay Description Inhibition assay using HCV protease.				US Patent US8476225 (2013) BindingDB Entry DOI: 10.7270/Q2M32TD9
					More data for this Ligand-Target Pair