BDBM97881 US8481536, 438::US8481536, 593

SMILES: COc1ccc(Cl)c(c1)-c1cc2nnc(Nc3ccc(cc3)C(=O)N3CCN(C)CC3)nc2cc1C

InChI Key: InChIKey=IOELWNQBJITVMV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM97881 (US8481536, 438 | US8481536, 593) Show SMILES COc1ccc(Cl)c(c1)-c1cc2nnc(Nc3ccc(cc3)C(=O)N3CCN(C)CC3)nc2cc1C Show InChI InChI=1S/C27H27ClN6O2/c1-17-14-24-25(16-21(17)22-15-20(36-3)8-9-23(22)28)31-32-27(30-24)29-19-6-4-18(5-7-19)26(35)34-12-10-33(2)11-13-34/h4-9,14-16H,10-13H2,1-3H3,(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM97881 (US8481536, 438 | US8481536, 593) Show SMILES COc1ccc(Cl)c(c1)-c1cc2nnc(Nc3ccc(cc3)C(=O)N3CCN(C)CC3)nc2cc1C Show InChI InChI=1S/C27H27ClN6O2/c1-17-14-24-25(16-21(17)22-15-20(36-3)8-9-23(22)28)31-32-27(30-24)29-19-6-4-18(5-7-19)26(35)34-12-10-33(2)11-13-34/h4-9,14-16H,10-13H2,1-3H3,(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair