BDBM97975 US8481536, 565

SMILES: CN(CCN1CCCC1)C(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(Cl)ccc(O)c2F)cc1

InChI Key: InChIKey=XLGZSWRWVOETRG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM97975 (US8481536, 565) Show SMILES CN(CCN1CCCC1)C(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(Cl)ccc(O)c2F)cc1 Show InChI InChI=1S/C28H28ClFN6O2/c1-17-15-19(24-21(29)9-10-23(37)25(24)30)16-22-26(17)32-28(34-33-22)31-20-7-5-18(6-8-20)27(38)35(2)13-14-36-11-3-4-12-36/h5-10,15-16,37H,3-4,11-14H2,1-2H3,(H,31,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.542	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
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