null

SMILES: CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)c1ccsc1

InChI Key: InChIKey=VVHCCEBTRHOKIX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM98618 (2-amino-1-ethyl-7-[3-hydroxy-3-(3-thienyl)but-1-yn...) Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)c1ccsc1 Show InChI InChI=1S/C20H20N4O3S/c1-4-24-17(21)15(19(26)22-3)16(25)14-6-5-13(23-18(14)24)7-9-20(2,27)12-8-10-28-11-12/h5-6,8,10-11,27H,4,21H2,1-3H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	20
Sanofi US Patent					Assay Description Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.				US Patent US8470847 (2013) BindingDB Entry DOI: 10.7270/Q2WD3Z67
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM98618 (2-amino-1-ethyl-7-[3-hydroxy-3-(3-thienyl)but-1-yn...) Show SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(C)(O)c1ccsc1 Show InChI InChI=1S/C20H20N4O3S/c1-4-24-17(21)15(19(26)22-3)16(25)14-6-5-13(23-18(14)24)7-9-20(2,27)12-8-10-28-11-12/h5-6,8,10-11,27H,4,21H2,1-3H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	20
Sanofi US Patent					Assay Description Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.				US Patent US8470847 (2013) BindingDB Entry DOI: 10.7270/Q2WD3Z67
					More data for this Ligand-Target Pair