BDBM98624 US8497376, 5
SMILES: CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)[C@H]1C[C@@]2(CO)CC[C@@](CO)(C1)O2
InChI Key: InChIKey=SVOYJTLJHABSCE-SDINYANESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse)) | BDBM98624 (US8497376, 5) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Pharmaceutica N.V. US Patent | Assay Description An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition. | US Patent US8497376 (2013) BindingDB Entry DOI: 10.7270/Q2RN36GW | |||||||||||
More data for this Ligand-Target Pair |