Enzyme Monomer Search

Marvin 2D Structure

Wt: 259.2 BDBM50202824	Wt: 297.2 BDBM50202818	Wt: 303.2 BDBM50202819	Wt: 301.3 BDBM50202822	Wt: 298.2 BDBM50202793
Wt: 301.3 BDBM50202794	Wt: 313.3 BDBM50202796	Wt: 302.2 BDBM50202799	Wt: 273.2 BDBM50202804	Wt: 259.2 BDBM50202805 Purchase
Wt: 313.3 BDBM50202809	Wt: 301.3 BDBM50202810	Wt: 273.2 BDBM50202812	Wt: 271.2 BDBM50202816	Wt: 301.3 BDBM50202815

Displayed 1 to 15 (of 274 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 19 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202809 (CHEMBL247462 \| N-(cyclopropylmethyl)-N-propyl-4-(2...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202794 (CHEMBL247256 \| N,N-dipropyl-4-(2,2,2-trifluoroacet...) Show SMILES CCCN(CCC)C(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202794 (CHEMBL247256 \| N,N-dipropyl-4-(2,2,2-trifluoroacet...) Show SMILES CCCN(CCC)C(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Inhibition of human recombinant MCD				Bioorg Med Chem 15: 4470-81 (2007) Article DOI: 10.1016/j.bmc.2007.04.025 BindingDB Entry DOI: 10.7270/Q2KH0N1C
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202793 (CHEMBL246033 \| N-(2-cyanoethyl)-N-ethyl-4-(2,2,2-t...) Show SMILES CCN(CCC#N)C(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202793 (CHEMBL246033 \| N-(2-cyanoethyl)-N-ethyl-4-(2,2,2-t...) Show SMILES CCN(CCC#N)C(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Inhibition of human recombinant MCD				Bioorg Med Chem 15: 4470-81 (2007) Article DOI: 10.1016/j.bmc.2007.04.025 BindingDB Entry DOI: 10.7270/Q2KH0N1C
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202815 (CHEMBL246029 \| N-(4-methylpentan-2-yl)-4-(2,2,2-tr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202815 (CHEMBL246029 \| N-(4-methylpentan-2-yl)-4-(2,2,2-tr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Inhibition of human recombinant MCD				Bioorg Med Chem 15: 4470-81 (2007) Article DOI: 10.1016/j.bmc.2007.04.025 BindingDB Entry DOI: 10.7270/Q2KH0N1C
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202796 (CHEMBL396690 \| N-(2-methylcyclohexyl)-4-(2,2,2-tri...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Inhibition of human recombinant MCD				Bioorg Med Chem 15: 4470-81 (2007) Article DOI: 10.1016/j.bmc.2007.04.025 BindingDB Entry DOI: 10.7270/Q2KH0N1C
St. John's University Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202796 (CHEMBL396690 \| N-(2-methylcyclohexyl)-4-(2,2,2-tri...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202810 (CHEMBL449355 \| N-hexyl-4-(2,2,2-trifluoroacetyl)be...) Show SMILES CCCCCCNC(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	679	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202819 (CHEMBL246035 \| N-ethyl-N-(2-methoxyethyl)-4-(2,2,2...) Show SMILES CCN(CCOC)C(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202804 (CHEMBL247463 \| N-isobutyl-4-(2,2,2-trifluoroacetyl...) Show SMILES CC(C)CNC(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202812 (CHEMBL397382 \| N,N-diethyl-4-(2,2,2-trifluoroacety...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202818 (CHEMBL245823 \| N-(furan-2-ylmethyl)-4-(2,2,2-trifl...) Show SMILES FC(F)(F)C(=O)c1ccc(cc1)C(=O)NCc1ccco1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202822 (CHEMBL248287 \| N-(3,3-dimethylbutyl)-4-(2,2,2-trif...) Show SMILES CC(C)(C)CCNC(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202816 (2,2,2-trifluoro-1-(4-(pyrrolidine-1-carbonyl)pheny...) Show SMILES FC(F)(F)C(=O)c1ccc(cc1)C(=O)N1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202805 (CHEMBL398019 \| N-isopropyl-4-(2,2,2-trifluoroacety...) Show SMILES CC(C)NC(=O)c1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202824 (CHEMBL395471 \| N-(4-(2,2,2-trifluoroacetyl)phenyl)...) Show SMILES CC(C)C(=O)Nc1ccc(cc1)C(=O)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50202799 (CHEMBL245402 \| N-(4-(2,2,2-trifluoroacetyl)phenyl)...) Show SMILES FC(F)(F)C(=O)c1ccc(NC(=O)N2CCOCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MBP fused human MCD				Bioorg Med Chem Lett 17: 1127-30 (2007) Article DOI: 10.1016/j.bmcl.2006.09.023 BindingDB Entry DOI: 10.7270/Q2MP52XX
Chugai Pharma USA, LLC. Curated by ChEMBL					More data for this Ligand-Target Pair