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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 230.3
BDBM50093654		Wt: 224.2
BDBM50093635Purchase		Wt: 235.2
BDBM50111086		Wt: 250.2
BDBM50111093		Wt: 235.2
BDBM50133759
Wt: 221.2
BDBM50133763		Wt: 255.7
BDBM50133767		Wt: 235.2
BDBM50133769		Wt: 227.3
BDBM50133770		Wt: 246.2
BDBM50133772
Wt: 221.2
BDBM50133774		Wt: 251.2
BDBM50133777		Wt: 220.2
BDBM50133778Purchase		Wt: 221.2
BDBM50133786		Wt: 248.3
BDBM50240829Purchase
Displayed 1 to 15 (of 1597 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 37 hits in this display   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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 0.0631n/an/an/an/an/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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 6.30n/an/an/an/an/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Effect on neuropeptide Y-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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 6.30n/an/an/an/an/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Effect on peptide YY-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell mem...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133769
PNG
(3-(5-m-Tolyl-1H-imidazol-2-yl)-pyridine | CHEMBL33...)
Show SMILES Cc1cccc(c1)-c1c[nH]c(n1)-c1cccnc1
Show InChI InChI=1S/C15H13N3/c1-11-4-2-5-12(8-11)14-10-17-15(18-14)13-6-3-7-16-9-13/h2-10H,1H3,(H,17,18)
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 14n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133767
PNG
(3-[5-(2-Chloro-phenyl)-1H-imidazol-2-yl]-pyridine ...)
Show SMILES Clc1ccccc1-c1c[nH]c(n1)-c1cccnc1
Show InChI InChI=1S/C14H10ClN3/c15-12-6-2-1-5-11(12)13-9-17-14(18-13)10-4-3-7-16-8-10/h1-9H,(H,17,18)
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 21n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133778
PNG
(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)
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 34n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133759
PNG
(3-(5-o-Tolyl-1H-imidazol-2-yl)-pyridine | CHEMBL33...)
Show SMILES Cc1ccccc1-c1c[nH]c(n1)-c1cccnc1
Show InChI InChI=1S/C15H13N3/c1-11-5-2-3-7-13(11)14-10-17-15(18-14)12-6-4-8-16-9-12/h2-10H,1H3,(H,17,18)
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 40n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133777
PNG
(3-[5-(3-Methoxy-phenyl)-1H-imidazol-2-yl]-pyridine...)
Show SMILES COc1cccc(c1)-c1c[nH]c(n1)-c1cccnc1
Show InChI InChI=1S/C15H13N3O/c1-19-13-6-2-4-11(8-13)14-10-17-15(18-14)12-5-3-7-16-9-12/h2-10H,1H3,(H,17,18)
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 56n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133770
PNG
(3-(5-Cyclohexyl-1H-imidazol-2-yl)-pyridine | CHEMB...)
Show SMILES C1CCC(CC1)c1c[nH]c(n1)-c1cccnc1
Show InChI InChI=1S/C14H17N3/c1-2-5-11(6-3-1)13-10-16-14(17-13)12-7-4-8-15-9-12/h4,7-11H,1-3,5-6H2,(H,16,17)
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 231n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133763
PNG
(3-(4-phenyl-1H-imidazol-2-yl)pyridine | 3-(5-Pheny...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1cccnc1
Show InChI InChI=1S/C14H11N3/c1-2-5-11(6-3-1)13-10-16-14(17-13)12-7-4-8-15-9-12/h1-10H,(H,16,17)
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 525n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133786
PNG
(2-(5-Phenyl-1H-imidazol-2-yl)-pyridine | CHEMBL325...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccn1
Show InChI InChI=1S/C14H11N3/c1-2-6-11(7-3-1)13-10-16-14(17-13)12-8-4-5-9-15-12/h1-10H,(H,16,17)
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 1.45E+3n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133774
PNG
(4-(4-phenyl-1H-imidazol-2-yl)pyridine | 4-(5-Pheny...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccncc1
Show InChI InChI=1S/C14H11N3/c1-2-4-11(5-3-1)13-10-16-14(17-13)12-6-8-15-9-7-12/h1-10H,(H,16,17)
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 1.53E+3n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50133772
PNG
(4-(2-Pyridin-3-yl-3H-imidazol-4-yl)-benzonitrile |...)
Show SMILES N#Cc1ccc(cc1)-c1c[nH]c(n1)-c1cccnc1
Show InChI InChI=1S/C15H10N4/c16-8-11-3-5-12(6-4-11)14-10-18-15(19-14)13-2-1-7-17-9-13/h1-7,9-10H,(H,18,19)
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 3.00E+3n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cells

Bioorg Med Chem Lett 13: 3593-6 (2003)


BindingDB Entry DOI: 10.7270/Q2DF6QKD
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50093654
PNG
(2,6-Dimethyl-4-piperidin-1-yl-5H-pyrrolo[3,2-d]pyr...)
Show SMILES Cc1cc2nc(C)nc(N3CCCCC3)c2[nH]1
Show InChI InChI=1S/C13H18N4/c1-9-8-11-12(14-9)13(16-10(2)15-11)17-6-4-3-5-7-17/h8,14H,3-7H2,1-2H3
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n/an/a 160n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assay

J Med Chem 43: 4288-312 (2000)


BindingDB Entry DOI: 10.7270/Q2C828J1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111086
PNG
(3-(5-Methyl-2-phenyl-1H-imidazol-4-yl)-pyridine | ...)
Show SMILES Cc1[nH]c(nc1-c1cccnc1)-c1ccccc1
Show InChI InChI=1S/C15H13N3/c1-11-14(13-8-5-9-16-10-13)18-15(17-11)12-6-3-2-4-7-12/h2-10H,1H3,(H,17,18)
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n/an/a 427n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111093
PNG
(2-(1H-Imidazol-4-yl)-3,4,5,6-tetrahydro-1,3-diaza-...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2C1)-c1c[nH]cn1
Show InChI InChI=1S/C15H14N4/c1-2-6-11-10(4-1)5-3-7-12-14(11)19-15(18-12)13-8-16-9-17-13/h1-2,4,6,8-9H,3,5,7H2,(H,16,17)(H,18,19)
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n/an/a 570n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50093635
PNG
(2-Methyl-6-phenyl-5H-pyrrolo[3,2-d]pyrimidin-4-yla...)
Show SMILES Cc1nc(N)c2[nH]c(cc2n1)-c1ccccc1
Show InChI InChI=1S/C13H12N4/c1-8-15-11-7-10(9-5-3-2-4-6-9)17-12(11)13(14)16-8/h2-7,17H,1H3,(H2,14,15,16)
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n/an/a 3.10E+3n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assay

J Med Chem 43: 4288-312 (2000)


BindingDB Entry DOI: 10.7270/Q2C828J1
More data for this
Ligand-Target Pair
Sodium channel protein type 8 subunit alpha


(Rattus norvegicus)		BDBM50133778
PNG
(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)
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n/an/a 3.22E+4n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay

Bioorg Med Chem Lett 22: 6401-4 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.067
BindingDB Entry DOI: 10.7270/Q2TX3GGK
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50133778
PNG
(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)
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n/an/a 4.06E+4n/an/an/an/an/an/a



Università degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique

Bioorg Med Chem 18: 7957-65 (2010)


Article DOI: 10.1016/j.bmc.2010.09.029
BindingDB Entry DOI: 10.7270/Q26973T7
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50133778
PNG
(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)
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n/an/a 4.06E+4n/an/an/an/an/an/a



Università degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method

Bioorg Med Chem 17: 3642-8 (2009)


Article DOI: 10.1016/j.bmc.2009.03.067
BindingDB Entry DOI: 10.7270/Q2GQ6XN5
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 398n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 0.501n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 845n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 0.400n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 3.20n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-fused human NY5 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 2


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 0.0631n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-fused human NY2 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 0.0398n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-fused human NY1 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
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n/an/an/an/a 5.10E+3n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 794n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 4n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 0.398n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 0.0398n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 443n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 4.5n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 5.01E+3n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 0.0300n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 4


(Homo sapiens (Human))		BDBM50240829
PNG
(CHEMBL3559801)
Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
PDB

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n/an/an/an/a 0.5n/an/an/an/a



Leipzig University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...

J Med Chem 60: 7605-7612 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00976
BindingDB Entry DOI: 10.7270/Q22B915R
More data for this
Ligand-Target Pair