Marvin 2D Structure

Wt: 340.2 BDBM50341830Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lethal(3)malignant brain tumor-like protein 3 (Homo sapiens (Human))	BDBM50341830 (5-Bromo-N-(5-(pyrrolidin-1-yl)pentylnicotinamide |...) Show SMILES Brc1cncc(c1)C(=O)NCCCCCN1CCCC1 Show InChI InChI=1S/C15H22BrN3O/c16-14-10-13(11-17-12-14)15(20)18-6-2-1-3-7-19-8-4-5-9-19/h10-12H,1-9H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to L3MBTL3 by chemiluminescent assay				J Med Chem 54: 2504-11 (2011) Article DOI: 10.1021/jm200045v BindingDB Entry DOI: 10.7270/Q2HH6KCP
					More data for this Ligand-Target Pair
Isoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4) (Homo sapiens (Human))	BDBM50341830 (5-Bromo-N-(5-(pyrrolidin-1-yl)pentylnicotinamide |...) Show SMILES Brc1cncc(c1)C(=O)NCCCCCN1CCCC1 Show InChI InChI=1S/C15H22BrN3O/c16-14-10-13(11-17-12-14)15(20)18-6-2-1-3-7-19-8-4-5-9-19/h10-12H,1-9H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to human L3MBTL1 by chemiluminescent assay				J Med Chem 54: 2504-11 (2011) Article DOI: 10.1021/jm200045v BindingDB Entry DOI: 10.7270/Q2HH6KCP
					More data for this Ligand-Target Pair
PHD finger protein 13 (Homo sapiens (Human))	BDBM50341830 (5-Bromo-N-(5-(pyrrolidin-1-yl)pentylnicotinamide |...) Show SMILES Brc1cncc(c1)C(=O)NCCCCCN1CCCC1 Show InChI InChI=1S/C15H22BrN3O/c16-14-10-13(11-17-12-14)15(20)18-6-2-1-3-7-19-8-4-5-9-19/h10-12H,1-9H2,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to PHF13 by chemiluminescent assay				J Med Chem 54: 2504-11 (2011) Article DOI: 10.1021/jm200045v BindingDB Entry DOI: 10.7270/Q2HH6KCP
					More data for this Ligand-Target Pair
Isoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4) (Homo sapiens (Human))	BDBM50341830 (5-Bromo-N-(5-(pyrrolidin-1-yl)pentylnicotinamide |...) Show SMILES Brc1cncc(c1)C(=O)NCCCCCN1CCCC1 Show InChI InChI=1S/C15H22BrN3O/c16-14-10-13(11-17-12-14)15(20)18-6-2-1-3-7-19-8-4-5-9-19/h10-12H,1-9H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Binding affinity to human L3MBTL1 assessed as dissociation constant by isothermal titration calorimetric assay				J Med Chem 54: 2504-11 (2011) Article DOI: 10.1021/jm200045v BindingDB Entry DOI: 10.7270/Q2HH6KCP
					More data for this Ligand-Target Pair