Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisomal sarcosine oxidase (Homo sapiens (Human)) | BDBM50052429 ((2S)-piperidine-2-carboxylate | (S)-pipecolate | L...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University Curated by ChEMBL | Assay Description determined in L-pipecolate oxidase from Rehsus monkey | J Med Chem 39: 3046-8 (1996) Article DOI: 10.1021/jm960331f BindingDB Entry DOI: 10.7270/Q20K2973 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proton-coupled amino acid transporter 1 (Homo sapiens (Human)) | BDBM50052429 ((2S)-piperidine-2-carboxylate | (S)-pipecolate | L...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 1.10E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting | Bioorg Med Chem 19: 6409-18 (2011) Checked by Author Article DOI: 10.1016/j.bmc.2011.08.058 BindingDB Entry DOI: 10.7270/Q2NZ882D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisomal sarcosine oxidase (Homo sapiens (Human)) | BDBM50291134 ((4S)-1,3-thiazinane-4-carboxylic acid | CHEMBL3586...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article | 3.60E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Time and concentration dependent inhibition of L-pipecolate oxidase was determined by the compound | Bioorg Med Chem Lett 7: 457-462 (1997) Article DOI: 10.1016/S0960-894X(97)00042-5 BindingDB Entry DOI: 10.7270/Q2D21XMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisomal sarcosine oxidase (Homo sapiens (Human)) | BDBM50069058 ((1R,2S,5S)-6-Oxa-3-aza-bicyclo[3.1.0]hexane-2-carb...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon State University Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of L-pipecolate oxidase(LPO) isolated from frozen Rhesus monkey liver | Bioorg Med Chem Lett 8: 739-44 (1999) BindingDB Entry DOI: 10.7270/Q22F7MKF | |||||||||||
More data for this Ligand-Target Pair |