Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclic AMP receptor protein (Vibrio cholerae O1 biovar El Tor str. N16961) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PCBioAssay | n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Specialized Biocontainment Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2HD7T8K | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kJ/mole | -TΔS° kJ/mole | ΔH° kJ/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -32.2 | -57.2 | 25.5 | 5.61 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -30.5 | -23.0 | -7.90 | 5.43 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -30.1 | -20.9 | -9.20 | 5.26 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -30.1 | -83.2 | 51.5 | 5.26 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -29.3 | -16.4 | -11.3 | 5.26 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -28.9 | -20.6 | -8.40 | 5.08 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -28.9 | -59.0 | 30.1 | 5.08 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -28.5 | -16.4 | -12.1 | 4.91 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -28.5 | -9.54 | -19.2 | 4.91 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -27.6 | -68.6 | 41 | 4.91 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -27.6 | -62.0 | 34.3 | 4.91 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
cAMP-activated global transcriptional regulator CRP (Escherichia coli) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -25.5 | -29.2 | 2.90 | 4.56 | 7.80 | 25 | |
Durham University | PLoS Biol 11: (2013) | |||||||||
Heat Shock Protein 90 (Hsp90) (Saccharomyces cerevisiae (Baker s yeast)) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -23.5 | 24.3 | -47.8 | 4.34 | 8 | 10 | |
University College London | J Mol Biol 392: 923-36 (2009) | |||||||||
Heat Shock Protein 90 (Hsp90) (Saccharomyces cerevisiae (Baker s yeast)) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -22.6 | 25.4 | -48 | 4.08 | 8 | 15 | |
University College London | J Mol Biol 392: 923-36 (2009) | |||||||||
Heat Shock Protein 90 (Hsp90) (Saccharomyces cerevisiae (Baker s yeast)) | BDBM10851 ((4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihy...) | GoogleScholar PDB | CHEBI KEGG PC cid PC sid PDB | -21.3 | 20.8 | -42.1 | 3.70 | 8 | 25 | |
University College London | J Mol Biol 392: 923-36 (2009) |