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3D structures from the PDB for "Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant V1/S" AND "BDBM18512"
(Proteins have >= 85% sequence identity and ligands are exact matches)


Seq IdentityJmol DisplayPDB Title
3QG2100%JmolPLASMODIUM FALCIPARUM DHFR-TS QRADRUPLE MUTANT (N51I+C59R+S108N+I164L, V1/S) PYRIMETHAMINE COMPLEX
1J3J100%JmolDouble mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP
3QGT>99%JmolCRYSTAL STRUCTURE OF WILD-TYPE PFDHFR-TS COMPLEXED WITH NADPH, DUMP AND PYRIMETHAMINE
3UM5>99%JmolDOUBLE MUTANT (A16V+S108T) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS-T9/94) COMPLEXED WITH PYRIMETHAMINE, NADPH, AND DUMP