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3D structures from the PDB for "Dihydrofolate reductase" AND "BDBM18050"
(Proteins have >= 85% sequence identity and ligands are exact matches)


Seq IdentityJmol DisplayPDB Title
1U70>99%JmolUNDERSTANDING THE ROLE OF LEU22 VARIANTS IN METHOTREXATE RESISTANCE: COMPARISON OF WILD-TYPE AND LEU22ARG VARIANT MOUSE AND HUMAN DIHYDROFOLATE REDUCTASE
1U7290%JmolUNDERSTANDING THE ROLE OF LEU22 VARIANTS IN METHOTREXATE RESISTANCE: COMPARISON OF WILD-TYPE AND LEU22ARG VARIANT MOUSE AND HUMAN DIHYDRFOLATE REDUCTASE TERNARY CRYSTAL COMPLEXES WITH METHOTREXATE AND NADPH
1DLS89%JmolMETHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE REDUCTASE WITH SUBSTITUTION OF LEUCINE 22: KINETICS, CRYSTALLOGRAPHY AND POTENTIAL AS SELECTABLE MARKERS
3EIG89%JmolCRYSTAL STRUCTURE OF A METHOTREXATE-RESISTANT MUTANT OF HUMAN DIHYDROFOLATE REDUCTASE