KEGG   Mycobacterium tuberculosis H37Rv: Rv2754c
Entry
Rv2754c           CDS       T00015                                 
Symbol
thyX
Name
(RefSeq) thymidylate synthase ThyX
  KO
K03465  thymidylate synthase (FAD) [EC:2.1.1.148]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00240  Pyrimidine metabolism
mtu00670  One carbon pool by folate
mtu01100  Metabolic pathways
mtu01232  Nucleotide metabolism
Module
mtu_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    Rv2754c (thyX)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Rv2754c (thyX)
Enzymes [BR:mtu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.148  thymidylate synthase (FAD)
     Rv2754c (thyX)
SSDB
Motif
Pfam: Thy1 CHASE3
Other DBs
NCBI-GeneID: 887766
NCBI-ProteinID: NP_217270
TubercuList: Rv2754c
UniProt: P9WG57
Structure
Position
complement(3067193..3067945)
AA seq 250 aa
MAETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKPNPKTATNAGY
LRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPP
GMEDDADLRHILTEAADAARATYSELLAKLEAKFADQPNAILRRKQARQAARAVLPNATE
TRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTE
VATSPLATEA
NT seq 753 nt   +upstreamnt  +downstreamnt
gtggccgagaccgcgccgctgcgcgtgcaactgatcgccaagaccgacttcttggcccca
cccgacgtgccctggaccaccgacgccgacggcggacccgcgctggtcgagttcgccggc
cgggcctgctatcagagctggtccaagcccaatcccaagaccgccaccaacgccggctac
ctccggcacatcatcgacgtcggacatttctcggtgctagagcatgccagcgtgtcgttc
tacatcaccgggatctcgcgatcgtgcacccacgagctgatccgccaccggcatttctcc
tactcgcagctctcccagcgctacgtacccgagaaggactcgcgggtcgtcgtgccgccc
ggcatggaggacgacgccgacctgcgccacatcctgaccgaggccgccgacgccgcccgc
gccacctacagcgagctgctggccaagctggaagccaagttcgccgaccaacccaacgcg
atcctgcgccgcaagcaggcccgccaagccgcccgcgcggtgctgcccaacgccaccgaa
acccgcatcgtggtgaccggcaactaccgggcctggcggcacttcatcgcaatgcgggcc
agcgagcacgccgacgtggaaatccggcgactggccatcgaatgcctgcgccagctcgcc
gccgtggcccccgcggtgttcgccgacttcgaggtgaccaccctggccgacggcaccgag
gtggcgaccagcccgttggcgaccgaagcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (37)   

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